NFL picks 2026: Full list of Week 6 predictions with confidence levels

ORCHARD PARK, NEW YORK - SEPTEMBER 17: Josh Allen #17 of the Buffalo Bills attempts to leap over Marcus Epps #1 of the Las Vegas Raiders during the second quarter at Highmark Stadium on September 17, 2023 in Orchard Park, New York. | Getty Images The NFL is back for Week 6 as the playoff picture slowly starts to gain some clarity. The playoff push heats up closer to Thanksgiving, but we’re starting to see teams position themselves for a run or reach a point where rebuilding might be in order. Some unexpected contenders include the Raiders and Browns in the AFC, and the Giants in the NFC. The 49ers, Chiefs, and Vikings all sit undefeated and in good shape heading into Week 6. On the other end of things, the Texans and Chargers are struggling in the AFC, while the Buccaneers, Cowboys, Eagles, and Rams are all scuffling in the NFC. This week opens with a significant inter-conference matchup between the Seahawks and Broncos on Thursday Night Football. Sunday brings Ravens-Browns and Bills-Raiders with some unexpected early playoff implications. The week closes with Cowboys-Packers on Sunday Night Football and Commanders-49ers on Monday Night Football. This week’s byes include the Bengals, Dolphins, Lions, and Vikings. I’m back for another week of picks as I remain entirely mediocre. Last week I went 7-7-1 and remain firmly at .500. I managed 2-1 on high confidence picks and 3-0-1 on my medium level picks, but 2-6 on low confidence picks sank me. Just a reminder that I pick games straight up with winners and losers, but I also provide a confidence level. I’ll pick each game’s winner and slot the picks based on confidence levels — high, medium, low, and no. A game with three asterisks (***) after it indicates a game where I’m picking the betting underdog to get the win. Whether you have to assign confidence points or not, this will help you know where I’m standing with the picks. And within each group, I’ve ordered them based on confidence within the confidence level. And also, I’m a 49ers fan, so every week you should take that pick with a grain of salt. High confidence Cardinals over Rams Patriots over Jets Bills over Raiders Colts over Titans 49ers over Commanders Medium confidence Chiefs over Chargers Ravens over Browns Jaguars over Texans Bears over Falcons Packers over Cowboys Broncos over Seahawks*** Low confidence Panthers over Eagles*** Buccaneers over Steelers*** Giants over Saints***

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