New egg yolk-free freezing solution enables rat IVF and live births

Fertility treatments are becoming more advanced, including through cryopreservation, or the freezing of eggs and sperm. However, studies involving animal sperm often use a lactose solution containing chicken egg yolk and OEP, a detergent containing sodium lauryl sulfate. The egg yolk carries the risk of microbial contamination and high batch variability, while the detergent has the potential to damage oocytes during in vitro fertilization.

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