Nanoneedle arrays map RNA in fresh tissue without sequencing or amplification

Recently, spatial omics has become a powerful tool, enabling researchers to see not only what molecules are present in a tissue, but also where they are located and how they are organized across cells, tissue structures and local microenvironments. This spatial context has deepened our understanding of cancer, neurobiology and immunology. Yet as the field advances, an important question remains: How many of these powerful technologies are ready for routine clinical use?

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