Fluorescent test speeds screening of thousands of enzyme variants that modify plant compounds

Many natural plant compounds have promising health-related properties, but their poor water solubility can limit how effectively they are absorbed and used. In previous work, researchers discovered an enzyme from Bacillus subtilis, called phenolic phosphate synthetase (BsPPS), that can attach phosphate groups to a broad range of phenolic compounds. This modification can help make these compounds more water-soluble and support the development of improved nutraceuticals and related products.

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