High-salt diet may drive fatty liver disease differently in lean people

Fatty liver disease is commonly associated with obesity, yet a growing number of people with normal body weight develop a severe form of the condition. Scientists at Duke-NUS Medical School have identified a distinct mechanism in a mouse model that may help explain why: Excess dietary salt can alter liver metabolism and trigger inflammatory pathways associated with lean metabolic dysfunction-associated steatohepatitis (MASH).

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