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HealthMedical Xpress

Dietary supplement may influence lung tumor growth differently in females and males

A study led by researchers at the UCLA Health Jonsson Comprehensive Cancer Center found that a dietary form of a naturally occurring molecule called calcium alpha-ketoglutarate, or Ca-αKG, reduced lung tumor growth in female mice and activated genes associated with better outcomes in women with lung cancer. The researchers also found that Ca-αKG had the opposite effect in male mice, where it was associated with larger tumors and increased tumor-cell proliferation.

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Dietary supplement may influence lung tumor growth differently in females and males — SignalPop