The body's warmth sensor is secretly a pain switch—blocking it may ease arthritis

Chronic pain, including arthritis pain, affects more than one-third of U.K. adults. Current painkillers such as methotrexate and nonsteroidal anti-inflammatory drugs (NSAIDs) work by damping down the immune system, which is overproducing inflammatory agents that cause pain, but relief is often short-lived and incomplete, and they can leave patients more vulnerable to infection.

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