Aging oxidation drives brain proteins into harmful condensates, study finds

An international research team that included Martín Hugo, a Serra Húnter lecturer in the Department of Biochemistry and Molecular Biology at the UAB, has described how two opposing chemical modifications of proteins, sulfenylation and persulfidation, regulate the behavior of key proteins in the brain during aging. The study was recently published in the journal Nature Structural & Molecular Biology.

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