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GLP-1 RAs produce significant weight loss in adults without diabetes, with newer treatments showing greater results
Every year there's a new 'greatest' shot on the market. Last year's greatest is already in the rearview.
An updated systematic review evaluating the efficacy and safety of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and coagonists among adults with overweight or obesity without diabetes found that, among currently available treatments, tirzepatide produced the greatest weight loss, while newer experimental drugs showed even larger effects.
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